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management syndrome apml causes classification differentiation elevation lactate lactic oncology rheumatology sjogrens typea typeb
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... initiation • Differential ... (sepsis), PE, DAH ... #management #hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
- Differential ... before beginning treatment ... cardiac output - Acute ... pulmonary edema ... peritonitis - Acute
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
renal tubular acidosis ... Nephrogenic DI Hematologic ... phenomenon (16%) MSK ... Adenocarcinoma Treatment ... Symptomatic: artificial tears
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