17 results
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... B-LNH), solid cancers ... Treatment: • ... Nicolas Taar ... #summary #rheumatology
Orthopedic Essentials - Spinal Trauma and Spine Classification 
DENIS THREE COLUMN CONCEPT
Anterior column:
Burst Fracture, Chance ... fractures: Don't cause ... able to weight bear ... Cauda equina Treatment ... #Orthopedics #diagnosis
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... center. ... Avoid meds that ... #Management #treatment ... #hematology
Syphilis - Clinical Manifestations and Treatment

1) Primary Syphilis
 • Direct lesion contact during sex is responsible
Syphilis - Clinical ... responsible for most cases ... Early latent year ... Late latent >1 year ... Syphilis #stages #diagnosis
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
Diagnosis = clinical ... in literature (NEJM ... (Cornelia NEJM ... Treatment of GCA ... them, but urgent rheumatology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... ) Classification ... lymph node biopsy (diagnostic ... Hodgkin Lymphoma Treatment ... #classification
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Autoimmune disease, Cancer ... epilepticus Treatment ... the underlying cause ... • Treatment of ... until cause identified
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
exclude other causes ... Clinical • Under-recognized ... support for patients clinically ... teratogenic GDMT meds ... management #cardiology #treatment
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
150 published cases ... Relapsing-remitting course +++ Clinical ... month at least 1 year ... leak #syndrome #diagnosis ... #rheumatology
Von Willebrand Disease Classification
Type 1 (Accounts for ~3/4 of cases):
 • Defect: Quantitative defect (i.e. not
Willebrand Disease Classification ... i.e. a total or near ... Bleeding: Severe (Clinically ... #Types #diagnosis ... #hematology