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diagnosis management rheumatology differential syndrome amyotrophic behcet cryofibrinogenemia disease encephalopathy gravis hematology lateral manifestations myasthenia myopathy myositis neuromyelitis nmo optica
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... AQP4-lgG disease; e.g ... Myositis, Comorbid autoimmune ... Manifestations #diagnosis #neurology ... #symptoms #signs
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
ulceration • Ocular ... skin injury) • Neurologic ... and diplopia) • Vascular ... spondyloarthritis • Ocular ... Leukemia, Lymphoma Ocular
Amyotrophic Lateral Sclerosis (ALS) Summary ALS: combination of the clinical examination finding of amyotrophy with the pathologic
of UMN and LMN signs ... 4) progressive muscular ... fasciculations Common Symptoms ... EMG: LMN Signs in ... Lateral #Sclerosis #neurology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Ocular- 50%: Ptosis ... Generalized fatigue - ALS ... Serologic and EMG ... - Peek sign ... diagnosis #management #neurology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... pulse deficits vascular ... pulmonary disease, and ocular ... ulcers, cutaneous, ocular ... Cogan syndrome: Ocular
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulin (CG ... Cryofibrinogenemia Symptoms ... Hyperviscosity, - Vascular ... associated with autoimmune ... pulmonary emboli, and ocular
Posterior Reversible Encephalopathy Syndrome (PRES) Overview Clinico-Radiological Syndrome, characterized by: • Headache • Seizures • Altered mental
may precede the neurologic ... /Sepsis/Shock, Autoimmune ... Neurological symptoms ... edema visualized as ... cortical lesions • Vascular
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Aldolase levels • EMG ... papules and Gottron sign ... ) • Shawl sign ... Polymyositis or ALS ... muscle disease/muscular
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