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HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
impairment • Mild ... activation -> diffuse ... through the blood-brain ... Clinical Presentation ... : The clinical
Leigh Syndrome 
History: 19-month-old girl with hypotonia, developmental 
delay, failure to thrive, and bilateral optic disc
History: 19-month-old ... Mitochondrial disorder ... various imaging patterns ... Leigh #Syndrome #Clinical ... #MRI #Brain #Diagnosis