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diagnosis differential algorithm anemia antiphospholipid aplastic apls chronic cll evaluation gap globulin hypercoagulable leukemia lymphocytic management mds monoclonal myelodysplasia myelodysplastic
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. TTP/HUS indicates thrombotic
Algorithm for workup ... /HUS indicates thrombotic ... hemolytic uremic syndrome ... thrombocytopenia, Hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
capillary leak syndrome ... Organomegaly+↑RBC/plt+, ↑thrombosis ... Hyperviscosity (Thrombosis ... Paraproteinemias #Hematology ... Differential #Diagnosis #Oncology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Constitutional Syndromes ... Constitutional Syndromes ... Aplastic Anemia: - Hepatitis ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Richter’s Syndrome ... leukemia • Sezary syndrome ... Leukemia #diagnosis #workup ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... formed or don’t work ... Workup: • Complete ... #diagnosis #hematology ... #oncology
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm INDICATIONS FOR TESTING: • Vascular thrombosis
Antiphospholipid Syndrome ... Hypercoagulable Workup ... TESTING: • Vascular thrombosis ... or small-vessel thrombosis ... Algorithm #diagnosis #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... changes (POEMS syndrome ... HBV, EBV, VZV, hepatitis ... gastric tumors • Hematology ... differential #diagnosis #hematology
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