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The Cell Cycle The cell cycle is the series of tightly regulated steps that controls cell growth
factor E2F (in the case ... factor (in the case ... proteins) that cause ... gene (TP53) to ... #cell #cycle #p53
Eosinophils (Eos) and hypereosinophilia (HE) Caused by eosinophilopoietic cytokines Common causes: - Drug reaction - Helminth infection -
hypereosinophilia (HE) Caused ... cytokines Common causes ... disease Rare causes ... : - B or T cell ... CD3-CD4+ T cells
Causes of Hypokalemia - Differential Diagnosis Algorithm Increased Loss - Increased GI Loss - Increased Urinary
Causes of Hypokalemia ... Transcellular Shift Into Cells ... - Increased Cell ... imports K+ into cells ... Diagnosis #Algorithm #causes
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
lymphocytes/Mature B cell ... smear: Smudge cells ... or basket cells ... disease • B cell ... AIHA • Pure red cell
Inflammatory mechanism of asthma. Airway epithelial cells exposed to activation stimuli, including allergens, viruses, and irritants,
Airway epithelial cells ... promote dendritic cell ... These T cells then ... induce B-cell class ... induce goblet cell
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
• Epithelial cells ... Renal tubular cells ... Dysmorphic red cells ... casts - Diagnostic ... • Hyaline casts
Acute Kidney Injury - Differential Diagnosis Framework PRERENAL: - Intrarenal vasoconstriction-hemodynamically mediated - Systemic vasodilation - Volume
Glomerular (red blood cells ... eosinophils/white blood cell ... casts on UA) - ... (renal tubular cell ... treating underlying cause
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
is entirely T-Cell ... exposure to allergen causes ... allergen-specific T-Cell ... exposure, because T-Cell ... harmful -> Th Cells
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
of ALL is of B-cell ... involvement • T-cell ... -> AML: Blast crises ... : Granulocytic cells ... form of large cell
Features of a Sickle Cell Crisis Sickle-cell disease - an autosomal recessive blood disorder. Characterized by red
Features of a Sickle Cell ... Crisis Sickle-cell ... These cells can ... Crises can be precipitated ... Sickle cell disease
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