13 results
Here is a quick guide on the common direct-acting antivirals (DAAs) for chronic hepatitis C virus
DAAs) for chronic hepatitis ... DAAs #Antivirals #table ... #treatment #hcv ... #medications #infectiousdisease ... #hepatology #HepC
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Severe Acute Liver Injury ... Drug-Induced liver injury ... - Autoimmune ... disease - Hemochromatosis ... #Differential #Hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
of Acute Liver Injury ... Toxic: Alcohol, Medication ... Other: NAFLD, Autoimmune ... GVHD • Toxic: Medication ... Acute #algorithm #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... , HSV, VZV • Medications ... Other: NAFLD, Autoimmune ... HELLP, Celiac disease ... Differential #Diagnosis #hepatology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Anticoagulant Medications ... Alcohol, Viral hepatitis ... , Autoimmune • ... Deficiencies #Summary #table ... comparison #diagnosis #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
duration), Several medications ... non-essential drug/HDS treatments ... Alcohol-related liver disease ... steatosis • Autoimmune ... Diagnosis #Algorithm #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis ... from subclinical disease ... pattern of liver injury ... regarding need for treatment ... Diagnosis #Management #Hepatology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
months without treatment ... underlying liver disease ... Drug-Induced Liver Injury ... (DILI) Viral Hepatitis ... Failure #Cirrhosis #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Autoimmune: ... Autoimmune hepatitis ... Chronic viral hepatitis ... #hepatitis #differential ... diagnosis #algorithm #hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... Indications Treatment ... with severe liver injury ... liver failure #HepatitisB ... #hepatology