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diagnosis hematology differential management oncology clinical druginduced lupus pathology treatment acute algorithm aml apl apml auer chronic cll coagulation comparison
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... features in most cases ... promyelocytic #leukemia ... APML #Pathology #Hematology ... #Clinical #Smear
Hypersegmented neutrophil in a case of acute myeloid leukemia. Dysplastic neutrophils are typically hypolobated but can be
neutrophil in a case ... acute myeloid leukemia ... AML #Clinical #Hematology ... #Pathology #Smear
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... peripheral blood smear ... patients if the cause ... dysplasia on the smear ... #Workup #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Leukemias Overview ... peripheral blood smear ... -> AML: Blast crises ... • Peripheral smear ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... • Most common leukemia ... • Peripheral smear ... #diagnosis #workup ... #oncology #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
myalgia, serositis, Kidney ... • Immunologic Workup ... Discontinuation of causal ... • Immunologic Workup ... comparison #table #rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... • Peripheral smear ... Treat primary cause ... Coagulation #diagnosis #causes ... treatment #management #hematology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
decrease in most cases ... Peripheral blood smear ... hematuria (without casts ... ThromboticThrombocytopenicPurpura #Diagnosis #Workup ... #Hematology
Polycythemia - Differential Diagnosis Algorithm Polycythemia itself isn’t a diagnosis. Like many things, it is a condition
an underlying cause ... oxygen sensing (at kidneys ... about secondary causes ... you’ll do a good workup ... Diagnosis #Algorithm #workup
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Peripheral Smear ... • Hairy Cell Leukemia ... Workup: • Complete ... Peripheral blood smear
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