11 results
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Pathogenesis and clinical ... injury, often from vascular ... Syndrome ->Cord ... herniation or tumour ... #signs #symptoms
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
Pathogenesis and clinical ... Carpal Tunnel Syndrome ... arrhythmia • Valvular ... Overproduction #diagnosis #signs ... #symptoms #endocrinology
Causes of Neuromuscular Weakness
 • Spinal Cord: Demyelinating Disease (MS), Epidural abscess, Infarction, Syringomyelia, Tetanus, Transverse
Weakness • Spinal Cord ... Myelitis, Trauma, Tumor ... Guillain-Barre syndrome ... heavy metals), Critical ... differential #diagnosis #neurology
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
• Acute stroke syndromes ... system: Brain tumor ... of the spinal cord ... Lack of UMN/LMN signs ... Differential #Diagnosis #neurology
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
neurological lesion: Clinical ... • Symptoms and signs ... Vascular/Blockage ... MCTD, Sjogren syndrome ... disorders #diagnosis #neurology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
skin injury) • Neurologic ... matter, spinal cord ... and diplopia) • Vascular ... interferon alfa, or tumor ... diagnosis #management #signs
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Forms of MS: • Tumor-like ... patients with clinically ... stimulation Clinical ... Progressive MS (Spinal cord
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Transverse Myelitis - Clinical ... • Bilateral signs ... Enhancement - TM and tumor ... diagnosis #management #neurology
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
combination of the clinical ... lateral sclerosis Pathophysiology ... multiple spinal cord ... 4) progressive muscular ... Lateral #Sclerosis #neurology
Causes of Secondary Hypertension - Workup and Differential Diagnosis
Approach (when evaluation should be done):
1. Severe or
hypertension and signs ... 109 mm Hg) with clinical ... renal bruit or signs ... Causes: • Vascular ... Vasculitis • Endocrinologic