15 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... leukapheresis - TLS ... • Pathophysiology ... #TLS #diagnosis ... #management #hematology
Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
neuroendocrine tumors ... Carpal Tunnel Syndrome ... diagnosis #signs #symptoms ... #endocrinology ... #pathophysiology
Ketosis Disorders
Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
Ketosis Disorders ... of re-feeding syndrome ... minimal ketosis but marked ... differential #diagnosis #management ... #endocrinology
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
Neurocognitive Disorder ... HIV dementia Pathophysiology ... • Depressive symptoms ... The clinical syndrome ... psychomotor slowing, marked
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Lateral Sclerosis (ALS ... lateral sclerosis Pathophysiology ... fasciculations Common Symptoms ... gastroenterologists, and social workers ... neurology #diagnosis #management
Adrenal Insufficiency - Diagnosis and Management Summary
Primary Adrenal Insufficiency:
Most Common Cause in the US: Autoimmune Adrenalitis
Other
Diagnosis and Management ... ketoconazole, etomidate) Symptoms ... including: pituitary tumor ... hypophysitis, Sheehan's syndrome ... #Endocrinology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
an autoimmune disorder ... with: - Thymic tumors ... thyroid, Sjogren syndrome ... Generalized fatigue - ALS ... Gravis #diagnosis #management
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
malignancy Pathophysiology ... pancreatic islet cell tumor ... Beckwith Wiedemann syndrome ... #Endocrinology ... #Treatment #Pathophysiology
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Cushing's Syndrome ... skin with stretch marks ... #Cushings #Syndrome ... Diagnosis #signs #symptoms ... #endocrinology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Forms of MS: • Tumor-like ... impairment, Mood disorder ... Signs and symptoms ... sclerosis #diagnosis #management