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Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
Hyperthyroidism Overview Clinical ... radioactive iodine uptake ... causes #diagnosis #differential
Differentiation of Causes of Hyperthyroidism According to Pattern of Radionucleotide Uptake Reduced uptake: • Thyroiditis • Exogenous
Radionucleotide Uptake ... Reduced uptake ... Focal increased uptake ... #radionuclide #uptake ... #differential #
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
Lactic Acidosis - Differential ... metabolism (e.g., uptake ... of lactate as a clinical ... a multitude of clinical ... Acidosis #Elevation #Differential
Hyperthyroidism - Differential Diagnosis Algorithm High/Normal Radioiodine Uptake - Autoimmune Thyroid Disease: • Grave's
Hyperthyroidism - Differential ... Normal Radioiodine Uptake ... Low Radioiodine Uptake ... #HighThyroid #Differential
Laboratory Evaluation of Patients for Thyroid Disease Hyperthyroidism: • Graves disease - TSH low; free T4
radioactive iodine uptake ... by suppressed uptake ... focal increased uptake ... by suppressed uptake ... #hyperthyroid #differential
Thyroid Function Tests (TFTs) and Interpretation • TSH, Free T4, Free T3 • T3 Uptake •
Free T3 • T3 Uptake ... laboratory #patterns #differential
Hypomagnesemia - Etiologies by Mechanism Decreased GI Uptake - Poor dietary intake (particularly common in alcoholics)
Decreased GI Uptake ... - Poor dietary intake ... Hypomagnesemia #Differential
Approach to the Diagnosis of Hyperthyroidism - Differential Diagnosis and Workup Algorithm • Secondary Hyperthyroidism (↑↔TSH,
Hyperthyroidism - Differential ... Iodine Scan - High Uptake ... Iodine Scan - Low Uptake ... Hyperthyroidism #Differential
Graves Disease - Autoimmune Hyperthyroidism Epidemiology: Most common cause of hyperthyroidism, Incidence peaks at 30-50 Diagnosis: 1 )
consider radioiodine uptake ... Clinical Presentation ... Methimazole/PTU (take ... Radioactive iodine (take
Hypokalemia Differential Diagnosis Algorithm Low intake • poor oral intake Renal loss • Medication • Hypomagnesemia •
Hypokalemia Differential ... Algorithm Low intake ... • poor oral intake ... #Hypokalemia #Differential
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