12 results
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
Autoimmune Myositis ... , holster sign, ... significant weakness after ... #Myositis #diagnosis ... #rheumatology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Arthritis Differential Diagnosis ... noninflammatory Signs ... Rheumatologic Disease ... #Differential #Diagnosis ... #MSK #rheumatology
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
Multi-system autoimmune ... skin thickening Signs ... Musculoskeletal: joint ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
heliotrope, shawl sign ... exclusion Necrotizing Autoimmune ... initially worsens after ... #differential #diagnosis ... #comparison #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral infection, autoimmune ... agglutination After ... CLL (older) • Autoimmune ... passage of red-brown urine ... hemolytic #anemia #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
rheumatologic diseases ... Arthritis: • Joint ... edema, active urine ... /LAC: • Renal artery ... #Rheumatology
Rheumatoid Arthritis - Signs and Symptoms
 • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans
 • Pulmonary:
Rheumatoid Arthritis - Signs ... Cardiac: Coronary artery ... Musculoskeletal: Joint ... #Symptoms #diagnosis ... #rheumatology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... Superficial temporal artery ... disturbance • Temp. artery ... Palpable purpura, joint ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... vesicular eruption - Joints ... Superficial temporal artery ... purpura: strong sign ... #rheumatology #
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
during or shortly after ... flank pain, dark urine ... RBCs (stored at 4C ... #Transfusion #diagnosis ... #management #hematology