11 results
Metabolic Alkalosis - Differential Diagnosis Algorithm - Urinary Chloride
 • Cl- responsive metabolic alkalosis
Metabolic Alkalosis ... Urinary Chloride • Cl ... Kidney loss of Cl ... - Loss of Cl- outside ... Cystic fibrosis) • Cl
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Primary Metabolic ... Diagnosis Algorithm ... hyperaldosteronism • Low Urine Cl ... NGT suction, Low Cl ... • High Urine Cl
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Metabolic Alkalosis ... Cl- responsive ... Kidney loss of Cl ... of Cl- outside ... Cystic fibrosis Cl
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... Diagnosis Algorithm ... hyperaldosteronism • Low Urine Cl ... NGT suction, Low Cl ... • High Urine Cl
Approach to Elevated Bicarbonate (HCO3)
Risk Factors for Hypercapnea? (Hx of COPD, OSA, sedative use, CNS/muscular disorders?)
(+)
Gas) (-) Likely Metabolic ... Alkalosis Urine ... Contraction Urine Cl ... Barter, or Gitelman Syndrome ... #alkalosis #algorithm
Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation: 
1. Acidemia or Alkalemia? 
2.
alkalosis ↓ ↑ ... (AG) = {Na - (Cl ... D D-lactate (short ... bowel syndrome, ... Diarrhea - Renal tubular
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... Diagnosis Algorithm ... hyperaldosteronism • Low Urine Cl ... NGT suction, Low Cl ... • High Urine Cl
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
resistance • Metabolic ... alkalosis • Familial ... disequilibrium syndrome ... irrigation • Management ... Inhibitors of Na+K+2Cl
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
alkalosis • Normal ... Hypochloremic metabolic ... (spot urine, calcium-creatinine ... , Renal tubular ... diagnosis #nephrology #management
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
breakdown of glycogen stores ... The metabolism of ... for Refeeding Syndrome ... #differential #algorithm ... #management #treatment