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Vesiculobullous Rashes - THE ALGORITHMIC APPROACH 
Vesiculobullous rashes provoke significant angst
in many physicians (Figure 5, page
Rashes - THE ALGORITHMIC ... rash and a fever ... hand-foot-and-mouth disease ... localized lesions and fever ... #Rash #Algorithm
Algorithm for Diagnosis of the Vesiculobullous Rash

Febrile, Diffuse Distribution:
 - Varicella,  Smallpox,  Disseminated, Gonococcal,
Algorithm for Diagnosis ... Rash Febrile ... Disseminated, Gonococcal, Infection ... Hand Foot & Mouth Disease ... #Vesicular #Rash
Infectious Joint Pain - Differential Diagnosis Algorithm 
Polyarticular Join Pain
 • Viral Myalgia
 • Viral Arthritis
Differential Diagnosis Algorithm ... • Secondary Syphilis ... & Symmetrical Rash ... (Measles- like rash ... #Orthopedics #Causes
Fever and Rash - Differential Diagnosis Framework
 • Viral: Measles, Infectious Mono (EBV, CMV), Acute HIV,
Fever and Rash - ... Viral: Measles, Infectious ... meningitis, Secondary syphilis ... gonorrhea, Rickettsial diseases ... #Rash #Differential
ID Approach to Fever and Rash - Diagnostic Algorithm
Central Maculopapular (most common):
Measles, Parvovirus 819 / EBV,
and Rash - Diagnostic ... PPGSS), Secondary syphilis ... drugs, lymphoma) Vesiculobullous ... angiomatosis, Sweet syndrome ... #Rash #Febrile
Natural History of Syphilis
Primary - 2-6 weeks after infection
 • Chancre, Regional lymphadenopathy
Early Latent ≤ 1
-6 weeks after infection ... ≤ 1 year after infection ... • Rash, Fever ... • Gummatous disease ... Meningovascular disease
Secondary Syphilis Rash
Secondary syphilis is the most contagious of all the stages of this disease, and
stages of this disease ... treatment, the infection ... ) ▪ Malaise, fever ... resembling rashes caused ... by other diseases
Vesiculobullous Skin Rash - Differential Diagnosis Algorithm
Vesicles Fragile/EasiIy Ruptured - Intraepidermal blisters, possibly crusts/erosions
 - Inflammatory
Vesiculobullous ... Skin Rash - Differential ... Diagnosis Algorithm ... foliaceus - Infectious ... #causes
SKIN RASHES 



Skin rashes can occur from a variety of factors, including infections, heat, allergens, immune
factors, including infections ... the presence of fever ... rashes into these classes ... petechiae; #purpura; #rash ... ; #vesiculobullous
Causes of Acute Onset Fever - Differential Diagnosis Algorithm
Viral:
 • Rhinovirus
 • Influenza Virus
 • Parainfluenza
Causes of Acute ... Diagnosis Algorithm ... Neuroleptic malignant syndrome ... • Sickle Cell disease ... #causes