15 results
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
mutations - Down syndrome ... chromosome 21) Signs ... seizure, primitive reflexes ... AlzheimersDisease #Dementia #pathophysiology ... #signs #symptoms
Positive Hoffmann's sign (finger flexor reflex)

Flexion and adduction of the thumb and flexion of the index
Positive Hoffmann's sign ... #Hoffmanns #sign ... clinical #hand #video ... physicalexam #msk #orthopedics ... #neurology #sports
Brudzinski’s Sign in Meningitis (first described in 19th century by Dr. Josef Brudzinski)

Brudzinski's sign is characterized
Brudzinski’s Sign ... Brudzinski's sign ... While the pathophysiology ... an involuntary reflex ... #PhysicalExam #Pediatrics
Prader-Willi Syndrome: Pathogenesis and clinical findings
 • Maternal uniparental disomy: inheriting 2 copies of maternal chromosome
Prader-Willi Syndrome ... Signs/Symptoms ... fractures • Short ... #genetics #pathophysiology ... #peds #pediatrics
Acute Spinal Cord Injuries: Pathogenesis and clinical findings
 • Anterior Cord Syndrome -> Anterior spinal artery
Anterior Cord Syndrome ... bladder and rectal reflex ... #diagnosis #pathophysiology ... #signs #symptoms ... #msk #orthopedics
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
Cauda Equina Syndrome ... lumbar spine Signs ... of normal leg reflexes ... #MSK #pathophysiology ... #signs
Lower Urinary Tract Infection: Pathogenesis and Clinical Findings

- Predisposing Factors:  Immunocompromised state, diabetes, elderly, female
elderly, female (short ... bladder, urinary reflux ... Signs/Symptoms ... UrinaryTractInfection #LUTI #Pathophysiology ... #Signs #Symptoms
Pott's Disease in Tuberculosis - Diagnosis and Management Summary
Epidemiology:
 - Typically from TB endemic areas
 -
cases Clinical Signs ... years - May have signs ... numbness, decreased reflexes ... Pathophysiology ... Residency @CMC_IM #Potts
Upper Urinary Tract infection (UUTI): Pathogenesis and Clinical Findings

Predisposing Factors:
 - Immunocompromised, Diabetes,
 - Elderly, Female
Elderly, Female (short ... bladder, urinary reflux ... UrinaryTractInfection #UUTI #Pathophysiology ... #Signs #Symptoms
Short Bowel Syndrome - Acute and Chronic Adverse Signs and Symptoms of Ileal Resection
 • Dehydration
Short Bowel Syndrome ... Chronic Adverse Signs ... and Symptoms of ... #Signs #Symptoms ... Ileal #Resection #pathophysiology