Characteristics of Common Lipid Disorders Polygenic hypercholesterolemia Atherogenic dyslipidemia • Frequently accompanied by central obesity or diabetes Familial hypercholesterolemia, Heterozygous • Family history of premature CHD, tendon xanthomas, comeal arcus Familial hypercholesterolemia, Homozygous • Family history of premature CHD, tendon xanthomas, comeal arcus affected individuals exhibit CHD by second decade of life Familial defective apoB-100 • Family history of CHD, tendon xanthomas Dysbetalipoproteinemia (type III hyperlipidemia) • PaImar xanthomas, tuberoeruptive xanthomas Familial combined hyperlipidemia • Family history, CHD, Family history, HLD Familial hyperapobetalipoproteinemia Hypoalphalipoproteinemia #lipid #disorders #diseases #comparison #table #defects #diagnosis #differential #hyperlipidemia