Causes of Hypomagnesemia
• Redistribution: IV glucose, Correction of diabetic ketoacidosis, IV hyperalimentation, Refeeding after starvation, Acute pancreatitis, Postparathyroidectomy (hungry bone syndrome), Osteoblastic metastasis (hungry bone syndrome)
• Extrarenal loss: Nasogastric suction (infrequent), Lactation, Profuse sweating, burns, sepsis, Intestinal or biliary fistula, Diarrhea
• Decreased intake: Alcoholism (cirrhosis), Malnutrition, poor intake, Small bowel resection, Malabsorption (steatorrhea)
• Renal loss: Ketoacidosis, Saline or osmotic diuresis, Potassium depletion, Phosphorus depletion, Familial hypophosphatemia, Tubulointerstitial renal disease
• Drugs: Loop diuretics, Aminoglycosides, Amphotericin B, Vitamin D intoxication, Alcohol, Cisplatin, Theophylline, Proton pump inhibitors, Calcineurin inhibitors (cyclosporine, tacrolimus)
• Endocrine disorders: Syndrome of inappropriate antidiuretic hormone secretion, Hyperthyroidism, Hyperparathyroidism, Hypercalcemic states, Primary or secondary aldosteronism
#Hypomagnesemia #Causes #differential #diagnosis #nephrology #magnesium #low
Chest Pain Diagnosis and Management Algorithm
STEMI:
- Hx: Pressure like CP, Radiation to arm/jaw, CAD risk factors
- PEX: Non-reproducible, Non-pleuritic, N/V/diaphoresis
Aortic Dissection:
- Hx: Sudden onset, severe, tearing CP, Risks: h/o Marfan, HTN, cocaine
- PEX: New murmur, Pulse deficit, Focal neuro deficit, Limb ischemia
Pulmonary Embolism:
- Hx: Sudden onset pleuritic CP, Dyspnea, PE risk factors
- PEX: Dyspnea, Leg pain/swelling, Wells score
Pericarditis:
- Hx: Pleuritic pain, Preceded by URI, underlying dz (SLE, uremia)
- PEX: Positional: worse supine, improves on sitting up, Pericardial friction rub, Fever, ↑WBC
Boerhaave's:
- Hx: Severe vomiting retrosternal CP, H/O recent instrumentation, EtOH, blunt trauma, caustic ingestion, HIV
- PEX: crepitus?
Pneumothorax:
- Hx: Acute pleuritic pain, Asthenic body, h/o trauma
- PEX: Decreased/absent breath sounds, Dyspnea, H/O COPD, asthma, CF, PCP
#ChestPain #Diagnosis #Management #Algorithm #differential
Treatment of Stable Narrow-Complex Tachycardia
Regular Rhythm:
• Attempt vagal maneuvers
• Give adenosine 6 milligrams IV push followed by 12 milligrams IV push if does not convert
- Repeat 12-milligram dose once
• Converts - Probably AVnRT or AVRT
- Observe and monitor
- Repeat adenosine if returns
- Control rate with AV nodal blocking agents (diltiazem or B-blockers)
• Does not convert - Possible atrial flutter, ectopic atrial tachycardia, junctional tachycardia
- Control rate (e.g., diltiazem or B-blockers, use B-blockers with caution in pulmonary disease or CHF)
- Treat underlying cause
Irregular Rhythm:
• Probable atrial fibrillation or possible atrial flutter or MAT
- Control rate (e.g., diltiazem or B-blockers, use B-blockers with caution in pulmonary disease or CHF)
- Treat underlying cause
#Stable #NarrowComplex #Tachycardia #Treatment #management #cardiology #algorithm
Typical therapeutic applications of Tetracyclines (Doxycycline)
Gram (+) cocci: Staphylococcus aureus (including methicillin-resistant strains), Streptococcus pneumoniae
Gram (+) bacilli: Bacillus anthracis
Gram (-) rods: Brucella species, Vibrio cholerae, Yersinia pestis
Anaerobic organisms: Clostridiunm perfringens, Clostridium tetani
Spirochetes: Borrelia burgdorferi, Leptospira interrogans, Treponema pallidum
Mycoplasma: Mycoplasma pneumoniae
Chlamydia: Chlamydia species
Other: Rickettsia rickettsii
#Tetracyclines #Doxycycline #indications #coverage #pharmacology #antibiotics