NSAIDS and COX Selectivity Relative selectivity of some commonly used NSAIDs. Data shown as the logarithm of their ratio of IC80 (drug concentration to achieve 80% inhibition of cyclooxygenase). COX-1 Selectivity, More to Less: • Ketorolac, Aspirin, Flurbiprofen, Ketoprofen, Indomethacin, Naproxen, Tolmetin, Ibuprofen, Fenoprofen COX-1 Selectivity, Less to More: • Piroxicam, Diclofenac, Celecoxib, Meloxicam, Etodolac #NSAIDs #COXInhibitor #cyclooxygenase #pharmacology #selectivity
