Typical Therapeutic Applications of Penicillin G Pneumococcal Pneumonia • Streptococcus pneumoniae is a major cause of bacterial pneumonia in all age groups. • Infection often occurs in an institutional setting in individuals who are ill from other causes. • Resistance to penicillin G has greatly increased worldwide due to mutations in one or more of the bacterial penicillin-binding proteins. Gonorrhea • Silver nitrate drops in the eyes prevent gonococcal ophthalmia in newborns. • Penicillinase-producing strains are treated using ceftriaxone, with azithromycin or spectinomycin as a backup. Syphilis • A contagious venereal disease that progressively affects many tissues. • A single treatment with penicillin is curative for primary and secondary syphilis. No antibiotic resistance has been reported. #PenicillinG #indications #management #applications
