Gastric Acid Secretion - Pathophysiology Chief cell - Pepsinogen Parietal cell - Acid, Intrinsic factor G cell - Gastrin Inhibitors: VIP, GIP, Somatostatin Phases of acid secretion: 1. Cephalic - Thought, sight or smell of food stimulate the vagus, producing acetylcholine 2. Gastric - Distension by food directly stimulates secretory cells and gastrin release 3. Intestinal - Passage of food into duodenum stimulates Gl hormone release #Gastric #Acid #Secretion #Pathophysiology #stomach
