Causes of Orthopnea - Differential Diagnosis Framework
• Fear and Anxiety
• Pleural Effusion
• Ascites
• COPD
• Hypothyroidism/Hyperthyroidism
• URTI
• Pulmonary Edema
• Severe Pneumonia
• Obesity/SIeep apnea
• Hypothyroidism
- Cardiogenic/Noncardiogenic pulmonary edema
- Diaphragmatic weakness
• Hyperthyroidism
- Cardiogenic pulmonary edema
- Diaphragmatic pulmonary edema
• Bilateral Diaphragmatic paralysis:
- Trauma
- Surgery
- Radiation
- Cervical manipulation
- CNS lesion: ALS, MS, Polio
- PNS lesion: Brachial plexus neuropathy, GBS, CIDP
- Myopathies
- Compressive mediastinal tumors
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