Argyll-Robertson Pupil on Physical Exam Small (myotic), irregular pupil that do not react to light but do react to accommodation. It is due lesion in the periaqueductal grey of the midbrain, where the fibers of the light reflex are close to the sympathetic pupilodilator fibers. THE ART OF MEDICINE @Medicalknowled1 #Argyll #Robertson #Pupil #PhysicalExam #clinical #video #neurology #ophthalmology