Satyendra Dhar, MD @DharSaty · 4 years ago
twitter@DharSaty
Concentrated Insulin Developed with the goal of easing therapy by reducing the volume & number of injections
twitter@DharSaty 
Concentrated Insulin

Developed with the goal of easing therapy by reducing the volume & number of injections and in some cases making use of altered pharmacokinetic and pharmacodynamic properties
Benefits: 
 • Large volumes insulin approaching 100 U impedes absorption & are more painful compared with smaller volume injections. Low volume lead to low variability, leading to lesser risk of hypoglycemia.
 • Pts who require > 200 U of insulin/ day are considered to have severe IR. 
 • Available in pens, associated with a lower risk of dosing errors. 
 • High patient acceptability & has the potential for decreased volumes & frequency of injections.
 • Shown to significantly improve glycemic control comparing pre- and post-intervention periods in patients switched from U-100 prandial insulin preparations to U-500 regular insulin.

Satyendra Dhar, MD @DharSaty

#Concentrated #Insulin #pharmacology #conversion
Satyendra Dhar, MD @DharSaty · 4 years ago
Hospital Medicine Clinical Assistant Professor The content and images on this website are provided for educational and informational purposes only and are not a substitute for professional medical advice, diagnosis, or treatment. The views expressed are those of the authors and do not necessarily reflect those of any affiliated institutions. While efforts are made to ensure accuracy and currency, medical knowledge is continually evolving, and errors or omissions may occur. Users are advised to independently verify information and seek guidance from qualified healthcare professionals for any medical decisions. By using this website, you acknowledge responsibility for your own clinical judgments, and the website and its contributors disclaim any liability arising from the use of its content. 👉 Follow 'Medical Infographics' on 👉 https://www.DharSaty.com
Related images