Prothrombin Time (PT) and Partial Thromboplastin Time (PTT) Prothrombin Time (PT) - Often Elevated in: • Vitamin K deficiency or antagonism (warfarin) • Factor VII deficiency or inhibitor • Liver disease Partial Thromboplastin Time (PTT) - Often elevated in: • Heparin use • Heparinized line • Factor XI, IX, VIII deficiency or inhibitor Both elevated in: • DIC • Underfilled test tubes • Factor X, V, II, fibrinogen deficiency or inhibitor Dr. Matt Tsai @thematttsai #PT #PTT #Prothrombin #Time #Partial #Thromboplastin #laboratory #hematology #diagnosis
