11 results
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Prothrombin Time ... Time (PTT) Prothrombin ... thematttsai #PT #PTT #Prothrombin
Liver Function Tests (LFTs)
 - Aspartate aminotransferase (AST) 
 - Alanine aminotransferase (ALT) 
 - Alkaline
(Direct) - Prothrombin
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
made in liver) Prothrombin ... Standardization of prothrombin
PAMPER - Prehospital Plasma during Air Medical Transport in Trauma Patients at Risk for Hemorrhagic Shock

N
a lower median prothrombin-time
Therefore, studies obtained at the initial presentation in the emergency department should evaluate for fibrinolysis with
levels, D-dimer, prothrombin
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
Humanized Fab fragment Prothrombin
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
Deficiency of prothrombin ... Acquired inhibitor of prothrombin
Antiphospholipid Syndrome (APLS) Testing - Hypercoagulable Workup Algorithm
INDICATIONS FOR TESTING:
 • Vascular thrombosis
Phosphatidylserine and Prothrombin ... IgG and IgMa • Prothrombin
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Leiden mutation - Prothrombin
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
aPTT Prolonged Prothrombin