Depostion of
glycosamineglycans
(mucin)
Filtration of albumin
Nat retention +
<
Edema
Effusion, hoarse voice, puffed-up face
Impaired cerebral development
Myxedema
Neuromuscular excitability
Sensory disturbances
Hyporeflexia
Lack of drive
Depression
Clouded consciousness
VitaminA
Sebaceous and sweat gland activity
Dry, scaly skin
Energy metabolism
Heat metabolism
Sensitivity to cold
Appetite!
Erythropoiesis
Renal blood flow
Glomerular filtration
Transport
Salt and water retention
Delayed breakdown of VLDL
Reduced bile secretion
VLDL 1
Cholesterol 4
Reduced lipolysis
Overweight
Intestinal motility
Constipation
Reflux esophagitis
Atherosclerosis
Cardiac contractility
Bradycardia
Protein synthesis
Elimination of drugs
#Glycogenolysis
#Gluconeogenesis
Hypoglycemia
In children: retarded longitudinal growth and delayed epiphyseal fusion somatotropin release
Small stature
Cretinism
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