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Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism Phosphate binders reduce hyperphosphataemia and hyperparathyroidism. Calcium-containing phosphate binders also improve hypocalcaemia. Calcitriol improves hypocalcaemia and hyperparathyroidism. Addition of cinacalcet to the first-line treatments inhibits PTH release. This decreases secondary hyperparathyroidism which reduces bone turnover and associated electrolyte disturbances. #Pharmacology #Pathophysiology #Secondary #Hyperparathyroidism #Sensipar #Cinacalcet #Calcitriol