13 results
Hormonal Regulation of the Blood Calcium concentration

#Calcium #Regulation #Parathyroid #Calcitonin #Calcitriol #PTH #Endocrinology #Pathophysiology #Hormones
Parathyroid #Calcitonin #Calcitriol
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
Calcitriol improves ... Sensipar #Cinacalcet #Calcitriol
Impact and Challenges With Vitamin D to Treat Secondary Hyperparathyroidism in Patients With Chronic Kidney Disease
suppresses SHPT Calcitriol ... or better than calcitriol ... or better than calcitriol ... Cholecalciferol #Calcitriol
OPTIMA Treatment Algorithm for Secondary Hyperparathyroidism
When indicated, the dose of a vitamin D (vit D) sterol
reached: intravenous calcitriol ... 2 μg TIW; oral calcitriol ... #Management #Calcitriol
Vitamin D Metabolism
Fat-soluble vitamin
Sources: dermal synthesis and food (dairy products, fish)
Active form: calcitriol (1,25-OH Vitamin D)
Main
) Active form: calcitriol
Hypomagnesemia (Serum level < 1.7 mg/dL)
Neuromuscular manifestations 
 • Tremor, tetany, seizures 
 • Weakness
Decreased synthesis of calcitriol
Duodenum
Jejunum
lleum
Colon
Na*
нсо;
Calcitriol
Aldosterone
#Aldosterone
Colon Na* нсо; Calcitriol
Hypercalcemia - Differential Diagnosis Algorithm
Elevated PTH (High or normal):
 • Primary Hyperparathyroidism
 • Familial Hypocalciuric Hypercalcemia
Low
PTH: • Elevated Calcitriol
Workup of Hypercalcemia - Differential Diagnosis Algorithm
High or Normal PTH:
 • Hyperparathyroidism: Parathyroid adenoma, Parathyroid hyperplasia,
diseases, Idiopathic calcitriol
Causes of Hypercalcemia
Parathyroid gland structure-related
 • Primary hyperparathyroidism
 • Parathyroid adenoma
 • Parathyroid hyperplasia
 • Parathyroid
prostate (release of calcitriol