OPTIMA Treatment Algorithm for Secondary Hyperparathyroidism When indicated, the dose of a vitamin D (vit D) sterol was reduced by approximately 50% in sequential steps until a minimum administered dose was reached: intravenous calcitriol, 0.5 μg three times per week (TIW); intravenous alfacalcidol, 1 μg TIW; intravenous paracalcitol, 2 μg TIW; oral calcitriol, 0.25 μg TIW; oral alfacalcidol, 0.25 μg/d. aThe dose of cinacalcet was reduced if a patient was not receiving vitamin D. #Management #Calcitriol #Secondary #Hyperparathyroidism #Optima #Algorithm
