HECK YES - Mnemonic for Organisms with AmpC Resistance H Hafnia alvei E Enterobacter cloacae C Citrobacter freundii K Klebsiella aerogenes Yes Yersinia enterocolitica Formerly SPICE / SPACE organisms. Gram-negative bacteria that have inducible, chromosomal beta-lactamase genes known as AmpC. Resistance may not be detectable initially, but appears after a period of exposure to beta-lactam antibiotics and 3rd generation cephalosporins. #HECKYES #SPICE #SPACE #Bacteria #Organisms #AmpC #Resistance #Antibiotics #Diagnosis #Microbiology #Mnemonic