Trypanosoma cruzi Reactivation in the Brain- ...Magnetic resonance images of the brain showed a mass measuring 8 by 7 by 6 cm in the corpus callosum and the white matter of the right parietal and occipital subcortical lobes (Panels A and B, with images obtained on T2-weighted imaging and on T1-weighted imaging, respectively, after the administration of contrast material). Cytologic examination of a brain aspirate revealed intracellular organisms (Panel C), with prominent kinetoplasts (masses of mitochondrial DNA) (arrow) visible within macrophages and astrocytes. The organisms were identified as Trypanosoma cruzi on the basis of partial protozoal 28S ribosomal RNA sequencing... #clinical #NEJM #trypanosoma #cruzi #reactivation #brain #MRI #radiology
