Daptomycin - Antibiotics Class Overview Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells. Rapidly cidal drug. Spectrum: only covers Gram positives including MRSA, strep, and Enterococcus/VRE. No gram negative activity. Used for: complicated skin/soft tissue infections, also being used more for MRSA bacteremia/endocarditis (due to cidal nature) #Pharmacology #Antibiotics #Review #Overview #Daptomycin
