17 results
Daptomycin  - Antibiotics Class Overview

Mechanism: Lipopeptide antibiotic – forms transmembrane channels and depolarizes cells.
Daptomycin - Antibiotics ... Review #Overview #Daptomycin
Daptomycin - Pharmacology

Mechanism of Action - Cyclic lipopeptide
Antimicrobial Spectrum - Gram Positive
Pharmacokinetics (Penetration)
Dose: 
 • SSTI:
Daptomycin - Pharmacology ... TheIDtrivia #Daptomycin
Antibiotics with MRSA Coverage

Oral: Doxycycline, Minocycline, Clindamycin, TMP-SMX
IV: Vancomycin, Daptomycin, Telavancin, Ceftaroline, Dalbavancin, Oritavancin, Tigecycline
Oral and
IV: Vancomycin, Daptomycin
Antibiotic Options for Treating MRSA Infections

PO: Doxycycline, Clindamycin, TMP-SMX, Linezolid
IV: Linezolid, Vancomycin, Ceftaroline, Daptomycin, Tigecycline

By Dr.
, Ceftaroline, Daptomycin
Mitral Valve Infective Endocarditis on POCUS Echocardiogram

IE & HIV & CD4<100 - Oh My!! Time for
Time for abx: daptomycin
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Creatine Kinase - Causes of Elevated CK Levels
Acute CK Elevation (Pain > Weakness):
 • RHABDOMYOLYSIS
fibrates, colchicine, daptomycin ... fibrates, colchicine, daptomycin
Antibiotics and CNS Diffusion

1. Drugs with good CNS diffusion:

- Fluoroquinolones, Fluconazole, voriconazole, Rifampin, Oxazolidinones, Metronidazole

2. Drugs
diffusion: - Daptomycin
Classification of Some Antimicrobial Agents by Their Sites of Action
Inhibitors of metabolism: Sulfonamides, Trimethoprim
Inhibitors of cell
ß-Lactams, Vancomycin, Daptomycin
Antibiotic Tissue Penetration

Blood Brain Barrier: Penicilins (IV), 3rd & 4th generation Cephalosporins (IV), Meropenem, TMP-SMX, Metronidazole,
antibiotics EXCEPT Daptomycin
Antibiotics - Mechanisms and Sites of Action 

Inhibit Cell Wall Synthesis or Function 
- Beta Lactams,
Lactams, Vancomycin, Daptomycin