Pathophysiology of The Nephron - Electrolyte and Water Exchange The nephron — electrolyte and water exchange. 180 L of water and 26000 mmol of sodium per day enter the nephrons via the afferent arterioles to the kidneys. Removal or addition of electrolytes results in the excretion of approximately I L of water and 60—180 mmol of sodium per day. #Pathophysiology #Nephrology #Nephron #Electrolytes #Reabsorption