Paracoccidioides brasiliensis Lymphadenitis: Paracoccidioidomycosis is a systemic fungal infection rare in the US, but endemic in Latin America. Head&neck, Lymph Nodes, and lungs are commonly involved. Lymph node entirely replaced with fibrosis (A) and well-formed granulomas (B). Yeast forms (arrows) can be seen within giant cells on H&E (C) or highlighted by GMS special stain (D). Note the characteristic pilot's wheel-like appearance of the budding yeasts. Contributor: Dr. Geronimo Jr. @EC_SocforHemepath @GeronimoJrLapac #Paracoccidioides #brasiliensis #Lymphadenitis #Pathology #LymphNode #Clinical #Microscopy