Here is a lymph node that is lymphoid-depleted, fibrotic, and burned-out, typical of late phase HIV lymphadenitis (so-called "pattern C"). Contributor: @KyleBradleyMD "Pattern C" in HIV Lymphadenitis: - Marked lymphoid depletion, atrophic follicles, fibrosis, and vascular proliferation (seen in lymph nodes from patients with late phase HIV infection) - "Pattern B" (not shown) is a transitional phase between pattern A (florid follicular hyperplasia) and pattern C #HIV #Lymphadenitis #PatternC #Pathology #Microscopy #LymphNode #Clinical
