Trichodysplasia spinulosa: follicles plugged w/ hyperkeratotic & parakeratotic debris, excessive inner root sheath differentiation towards keratinization. Enlarged cytoplasmic trichohyalin granules. EM shows intranuclear icosahedral polyomavirus inclusions! 

 -Silvija Gottesman MD
@SGottesmanMD

#Trichodysplasia #spinulosa #Pathology #Microscopy #Dermatology #Clinical
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