Congenital Cytomegalovirus Infection- Ultrasonographic images showed ventricular dilatation in the fetal brain, and T2-weighted magnetic resonance imaging revealed ventriculomegaly (Panel A) and cerebellar hypoplasia. Maternal serum immunoassay was positive for cytomegalovirus (CMV) IgG and IgM antibodies...Computed tomographic scans of the newborn’s brain showed ventricular dilatation, parenchymal hypoplasia with polymicrogyria, and periventricular calcifications (Panel B, arrows). Immunohistochemical testing of the placenta was positive for CMV, and polymerase-chain-reaction testing of the newborn’s urine revealed CMV DNA — findings that confirmed congenital CMV infection. Congenital CMV infection can be asymptomatic, or symptoms can include growth restriction, hematologic disorders, and sensorineural developmental disorders that range in severity from mild to severe... #clinical #NEJM #radiology #MRI #CT #computed #tomography #congenital #cytomegalovirus #infection #CMV
