Causes of Prolonged Emergence - Anesthesiology
Prolonged Drug Action:
• Overdose
• Hypothermia (< 33 C)
• Incr sensitivity
• Decr protein binding
• Redistribution
• Drug interaction
Metabolic Causes:
• Hypoxia / hypercapnia
• Organ dysfunction
— hepatic
— renal
— endocrine
• Hypoglycemia / hyperglycemia
• HONK / diabetic ketoacidosis
• Electrolyte imbalance:
— hyponatræmia
— hypocalcæmia
— hypomagnesæmia
• Hypothermia (< 33 C)
• Sepsis
• Alcohol
Neurologic Injury:
• Intracranial:
— hæmorrhage
— contusion
• Cerebral embolus / ischæmia
• Seizure:
— subclinical
— post-ictal state
• Incr intracranial pressure
• Pneumocephalus
Mark Harris, MD MPH @ https://twitter.com/MarkHarrisMD
#Prolonged #Emergence #Anesthesiology #Causes #Differential
