5 P’s Mnemonic for Symptoms in Acute Intermittent Porphyria Painful Abdomen - Colicky pain, sometimes out of proportion to exam. Psychological Disturbances - Anxiety, depression, psychosis, hallucinations, paranoia Pink (Port-wine) Urine - Due to accumulation of porphobilinogen and uroporphyrin. Can turn dark red-brown after exposure to light. Polyneuropathy - Peripheral neuropathy, motor more common than sensory. Precipitated by drugs/alcohol - Barbiturates, alcohol, sulfa drugs, stress or hormonal (menstrual) changes. #5Ps #5P #Ps #Mnemonic #Acute #Intermittent #Porphyria #AIP #Diagnosis
