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Effect of Dexmedetomidine on Mortality and Ventilator-Free Days in Patients Requiring Mechanical Ventilation With Sepsis JAMA. 2017;317(13):1321-1328 https://jamanetwork.com/journals/ja Conclusions: Among patients requiring mechanical ventilation, the use of dexmedetomidine compared with no dexmedetomidine did not result in statistically significant improvement in mortality or ventilator-free days. - Visual Abstract by Dr. Jonny Wilkinson @Wilkinsonjonny #DESIRE #Dexmedetomidine #Mortality #MechanicalVentilation #CriticalCare #EBM #VisualAbstract