Asboe-Hansen sign (also known as "indirect Nikolsky sign" or "Nikolsky II sign") Update View High-Res Mp4 Video Version here: https://www.grepmed.com/images/1042 Asboe-Hansen sign is the extension of an unruptured blister with the application of pressure. Best-detected by drawing a margin around the bulla prior. Asboe-Hansen sign is a useful clinical tool for diagnosing toxic epidermal necrolysis (TEN). Asboe-Hansen sign can be employed to generate a fresh bulla for lesional skin biopsy in the evaluation of TEN.
