Sites of Action of Drugs that Interfere with the Renin-Angiotensin-Aldosterone system #ReninAngiotensinAldosterone #RAAS

Pathophysiology of the Renin-angiotensin-aldosterone system (RAAS) and inhibitors #Pathophysiology #Pharmacology #RAAS #Renin #Angiotensin #Aldosterone #System #ACEInhibitors

Flowchart of the function of the renin-angiotensin aldosterone system (RAAS) #renin #angiotensin #aldosterone #system #RAAS #system #algorithm #pathophysiology

Renin-Angiotensin-Aldosterone System (RAAS) The kidneys produce renin in response to low blood pressure or low plasma Na concentrations. Renin acts on angiotensin in plasma to form angiotensin I. Angiotensin I is converted to angiotensin II in the lungs by the action of angiotensin-converting enzyme (ACE). Angiotensin II acts as a hormone and a neurotransmitter on different organs to produce changes that help restore blood pressure and Na+. #Pathophysiology #RAAS #Renin #Angiotensin #Aldosterone #System

Renin-Angiotensin-Aldosterone System (RAAS) #Pathophysiology #RAAS #Renin #Angiotensin #Aldosterone #System

Renin-Angiotensin-Aldosterone System (RAAS) #RAAS #Renin #Angiotensin #Aldosterone #System #Pathophysiology

Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS) This is a very common pathway that clinicians should definitely know. The end point is aldosterone which does a lot of different things not listed here, but the main takeaway is that the RAAS system ends with excreting potassium while retaining sodium, which causes increased blood pressure. The 4 RAAS inhibiting drug classes (Aliskiren, ACEI, ARB, and Aldosterone Antagonists), all block some part of this pathway, ending with the reversed result of excreting sodium while retaining potassium. This decreases blood pressure because of the sodium excretion, BUT will increase potassium retention, which is why potassium is an important monitoring parameter to avoid harmful hyperkalemia. An easy way to remember this is spironolactone is categorized as an Aldosterone antagonist AND a potassium-sparing diuretic, which means it increases potassium, just like all of the RAAS inhibiting drugs. Jarred Prudencio, PharmD - https://www.instagram.com/ambcarerx #ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology #Renin #Angiotensin #Aldosterone

Macula Densa Pathway - Physiological Pathways, Feedback Loops, and Pharmacological Regulation of the Renin-Angiotensin-System #MaculaDensa #Pathophysiology #Nephrology #Renal #Pharmacology #RAAS

HIV/AIDS Medications - Targets of Action Fusion inhibitors Inhibitors of reverse transcriptase Inhibitors of HIV protease #HIVAIDS #pharmacology #targets #action

Nephron Pathophysiology - Diuretic Sites of Action Diuretics 1) Acetazolamide/canagliflozin 2) Osmotic agents (mannitol, urearetics) 3) Loop agents (eg, furosemide) 4) Thiazides 5) Aldosterone antagonists 6) ADH antagonists 7) Adenosine #Nephron #Pathophysiology #Diuretics #Sites #Action #nephrology #pharmacology

Antibiotic Pharmacology - Sites of Action Cullen Lilley, MS, MDxT(AAB) @cullen_lilley #Antibiotics #Pharmacology #Sites #Action #mechanism