Diagnosis and Management of Hypocomplementemic Urticarial Vasculitis (HUV) Diagnosis of HUV 1) Chronic urticaria 2) Leukocytoclastic vasculitis 3) Hypocomplementemia (C3 and/or C4) Therapeutic management 1st-line therapy - Hydroxychloroquine, colchicine or disulone 2nd-line therapy - GCs <0.5 mg/kg/day Refractory and/or relapsing - Azathioprine, MMF, cyclophosphamide Alternative agents - Rituximab, anti-IgE, anti-IL-1 Dr. Benjamin Terrier @TerrierBen #Hypocomplementemic #Urticarial #Vasculitis #HUV #Diagnosis #Management #Rheumatology
