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Diagnosis and Management of Hypocomplementemic Urticarial Vasculitis (HUV)

Diagnosis of HUV
1) Chronic urticaria 
2) Leukocytoclastic vasculitis 
3)
Urticarial Vasculitis (HUV ... Diagnosis of HUV ... Urticarial #Vasculitis #HUV
Pathophysiology of Hypocomplementemic Urticarial Vasculitis

C1q/anti-C1q antibiody ->
Immune Complex Formation - Complement Pathway Activation (C3a and C5a)
Urticarial #Vasculitis #HUV
SCORTCH Congenital Infections Mnemonic
S - Syphilis
C - CMV
O - Other
R - Rubella
T - Toxoplasmosis
C - Chickenpox
Varicella) H - HSV ... , HIV, HTLV-1, HBV ... , HCV #SCORTCH
Infection-Related Cancers
Viruses:
 • HPV - Cervical, anogenital, head and neck, skin cancer
 • HTLV-1 - Adult
Cancers Viruses: • HPV ... T-cell Leukemia • HIV ... cell carcinoma • HBV ... / HCV - Hepatocellular ... carcinoma • HHV
Elevated Transaminases / Transaminitis - Differential Diagnosis

 • Infectious: HAV, HCV, HEV, EBV, HSV, CMV
 •
• Infectious: HAV ... , HCV, HEV, EBV, ... HSV, CMV • Neoplasm
IDSA - Prophylaxis to Prevent First Episode of Opportunistic Disease in HIV-AIDS
 • Pneumocystis pneumonia (PCP)
Opportunistic Disease in HIV-AIDS ... Papillomavirus (HPV ... Hepatitis A virus (HAV ... Hepatitis B virus (HBV
IDSA - Prophylaxis to Prevent First Episode of Opportunistic Disease in HIV-AIDS
 • Pneumocystis pneumonia (PCP)
Opportunistic Disease in HIV-AIDS ... Papillomavirus (HPV ... Hepatitis A virus (HAV ... Hepatitis B virus (HBV
Oral Cavity Lesions in a patient with HIV/AIDS
White plaque
 - Pseudo-membranous candidiasis
 - Oral hairy leukoplakia
a patient with HIV ... candidiasis - HSV ... Mass - Wart (HPV
Chronic Hepatitis B - Diagnosis and Management Algorithm

• Who to treat: Essentially treat the pts with
pts with chronic HBV ... phases of chronic HBV ... Quant HBV DNA. ... , HCV. ... HAV immunity; Liver
Clinical Manifestations of Human Herpes Viruses (HHV)

Herpes simplex virus 1	HSV-1	Frequently subclinical (80-90%) Oral lesions (10-20%) congenital
Herpes Viruses (HHV ... simplex virus 1 HSV ... simplex virus 2 HSV ... herpes virus 6 HHV ... herpes virus 7 HHV