Treatment of Non-hepatitis C virus Cryoglobulinemia Vasculitis - French Vasculitis Study Group MONOCLONAL CRYOGLOBULINEMIA (TYPE 1) IgM monoclonal component • Target lymphoplasmacytic proliferation (CD20+) • Rituximab, obinutuzumab, bendamustine, chloraminophene IgG monoclonal component • Target plasma cells (CD20-) • Alkylating agents, bortezomib, thalidomide or lenalinomide MIXED CRYOGLOBULINEMIA (TYPES II AND III) Glucocorticoids Immunosuppressive or immunomodulatory agents if severe and/or refractory disease ± Plasma exchanges Dr. Benjamin Terrier @ https://twitter.com/TerrierBen #NonHCV #Cryoglobulinemia #Vasculitis #Management #Rheumatology #Monoclonal #Mixed #Cryoglobulinemic
