Dyspnea - Considerations with Malignancy Directly Malignancy Related: - Lymphangitic spread to lung - Malignant pleural effusion - Malignant pericardial effusion - Lung metastases Treatment Related: - Chemotherapy pneumonitis - Cardiomyopathy (anthracycline) - Hemorrhagic myocarditis (cyclophosphamide) - Coronary Vasospasm (cepecitabine) - Radiation pneumonitis - Radiation induced disease of: - Heart valves - Pericardium - Coronary arteries - Conduction system - Therapy-related malignancy - Cytopenias (anemia) Changes in Pre-Test Probability: - Immunosuppression —> atypical bugs - Hypercoagulable -> PE Based On: https://www.nejm.org/doi/full/10.1056/NEJMcps1414168 #dyspnea #algorithm #differential #diagnosis #oncology #cancer #malignancy

A rhabdomyolysis framework inspired/adapted from an @NEJM CPS and @UpToDate. - Traumatic - Non-Traumatic Exertional - Non-Traumatic, Non-Exertional #rhabdomyolysis #diagnosis #algorithm #differential

Recurrent / Breakthrough DVT During Anticoagulation Subtherapeutic Anticoagulation Hypercoagulable State - Antithrombin deficiency - Hypercoagulability ot Ca - Behcet's disease - APLS - MPN/PNH Anatomic / Structural - Pelvic masses - May-Thurner syndrome - Congenital agenesis of IVC #Breakthrough #Recurrent #DVT #VTE #anticoagulation #hematology #differential #algorithm

Diagnostic Schema for Hyperferritinemia Pearl: Diseases associated with extreme elevations: 1. HLH 2. Still's disease 3. Systemic histoplasmosis #Ferritin #Hyperferritinemia #Algorithm #Differential #Diagnosis #Hematology