COVID-19 Clinical Presentation and Labs Common Symptoms • Fever in >75% at some point (~50% on admission) • Cough 45-80% (dry or productive) • SOB 20-40% • Myalgias 10-50% • Triad of fever, cough, SOB in only 15% Less Common Symptoms • URI symptoms (HA, sore throat, rhinorrhea) <15% • GI symptoms: N/V <10%, diarrhea <25% Routine Labs • Median WBC 4.7 with leukopenia in 17-54% and leukocytosis in <25% • Lymphopenia in 33-85% • Median platelets normal, with slight decrease in <35% • AST/ALT increase in 4-35% Biomarkers • CRP increased in 61-86% • LDH increased in 27-75% • Procalcitonin > 0.5 in 5-10% (but 14% if severe, 24% if ICU) UCSF Grand Rounds March 20 2020 #Presentation #Labs #Workup #Diagnosis #Symptoms #Signs #COVID19