Azithromycin - since there has been a lot of noise around chloroquine/hydroxychloroquine, thought we can take a quick review of azithromycin since it is being used in combination with hydroxychloroquine as one of the investigational treatments for COVID-19…

Note azithromycin has a long half-life of about 68 hrs (or more) and is an inhibitor of P-glycoprotein/ABCB1 so watch for potential DIs with colchicine, dabigatran, edoxaban, ranolazine, etc. Also, don't forget about increased QT prolongation risk when used in combo with chloroquine or hydroxychloroquine‼️

#Azithromycin #Zithromax #Macrolides #InfectiousDiseases #COVID19 #Coronavirus #Treatment #Management #Pharmacology #DrugInteraction #Pandemic
PharmD, BCGP, BCMTMS, BCACP @RxKeySlides · 5 years ago
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