Here is a quick IV catheter and flow rate reference chart (follower requested info)... - *For Educational Purposes Only* #IVCatheter #FlowRate #Chart

Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require phosphate binding agents since they are not able to effectively excrete phosphate. Generally, the initial dose is based on serum phosphate levels and doses should be adjusted to lower phosphate levels toward the normal range (KDIGO). Note not listed are aluminum-based phosphate binder (use has fallen out of favor due to safety reasons) and calcium carbonate form. The use of calcium-based phosphate binders is restricted due to hypercalcemia (KDIGO). *For Educational Purposes Only* #CKD #Nephrology #PhosphateBinders #Hyperphosphatemia #Dose #Dosing #Pharmacology #Maximum

Ivermectin. Old anti-parasitic agent making a comeback with recent headlines from in-vitro study that showed antiviral activity against SARS-CoV-2, the virus causing COVID-19. In preparation for another wave (like chloroquine/HCQ), here is a quick overview of ivermectin… #COVID19 #Coronavirus #SARS-CoV-2 #Pandemic #Outbreak #InfectiousDiseases #CriticalCare #EmergencyMedicine #Pharmacology #Treatment #Virus #Antiviral #Management #Ivermectin #Antiparasite

Azithromycin - since there has been a lot of noise around chloroquine/hydroxychloroquine, thought we can take a quick review of azithromycin since it is being used in combination with hydroxychloroquine as one of the investigational treatments for COVID-19… Note azithromycin has a long half-life of about 68 hrs (or more) and is an inhibitor of P-glycoprotein/ABCB1 so watch for potential DIs with colchicine, dabigatran, edoxaban, ranolazine, etc. Also, don't forget about increased QT prolongation risk when used in combo with chloroquine or hydroxychloroquine‼️ #Azithromycin #Zithromax #Macrolides #InfectiousDiseases #COVID19 #Coronavirus #Treatment #Management #Pharmacology #DrugInteraction #Pandemic

Anticoagulation Review. There are other bleeding risk assessment tools, but HAS-BLED is more commonly used. HTN defined as having SBP greater than 160 mmHg. Bleeding includes history or predisposition. Examples of drugs that increase bleeding include antiplatelets or NSAIDs and alcohol use of having more than 8 servings/week. *For Educational Purposes Only* #Anticoagulation #Anticoagulant #Bleeding #Risk #Tool #Assessment #Cardiology #SideEffects #Symptoms #Signs

COVID-19 review…here is a list of some of the drugs that are currently being used or being investigated for COVID-19. Also, WHO recently announced it is leading a new large multinational study, SOLIDARITY to establish the most effective treatments for COVID-19. Not much more information about the study design is given, but here are the 4 drug study arms to be included in this robust study… *For Educational Purposes Only* #COVID19 #CoronaVirus #Treatment #Management #Pandemic #Outbreak #InfectiousDiseases #Pharmacotherapy #Pharmacology #CriticalCare #EmergencyMedicine

With the recent publication of the FDA Guidance on alcohol-based hand sanitizer compounding, I thought to post the 2 formulations that are consistent with both the FDA and WHO recommendations. FDA is also encouraging pharmacists to compound these in light of current COVID-19 pandemic and hand sanitizer shortage. *For Educational Purposes Only* #COVID19 #Coronavirus #Compounding #Pharmacology #HandSanitizer

Levothyroxine tablet strengths are also color coded. Depending on the tablet shape (round vs oval) and generic manufacturer, there might be a slight variation. #Levothyroxine #Synthroid #ThyroidDisorder #ColorCoded #Endocrinology #Pharmacology #Hypothyroidism

Warfarin tablet strengths are color coded. There might be a slight variation depending on the generic manufacturer. #Warfarin #Coumadin #Cardiology #BloodClot #Color-Coded #Pharmacology #PrimaryCare #Anticoagulation #Anticoagulant

*Coronavirus Update*: investigational remdesivir for the treatment of COVID-19. Here is a quick highlight of two Phase 3 RCTs, evaluating the safety and efficacy of remdesivir. Initiation of these two studies were announced yesterday with the FDA’s rapid review and acceptance of IND (investigational new drug) filing of remdesivir. For more information check out ‪clinicaltrials.gov‬. #Coronavirus #Covid-19 #covid19 #2019-nCov #RespiratoryDisease #Pulmonology #Treatment #NovolCoronavirus #ClinicalTrial #InfectiousDisease #Virology #Outbreak #Remdesivir